August 11, 2022

Amgen Wins Approval for Pathbreaking Lung Cancer Drug

A pathbreaking pill for lung cancer from Amgen Inc. was approved by the U.S. Food and Drug Administration, adding a new potential blockbuster to the biotech giant’s aging stable of drugs.

The drug, called Lumakras, was approved Friday to treat a portion of lung cancer patients with a particular genetic mutation who have already tried other therapies.

The mutation, known as KRAS, is among the most common found in cancers, but researchers struggled for so many years to find a medicine that can treat it that the mutation came to be considered “undruggable.”

The FDA’s approval, which has sped through clinical trials since the first encouraging results in 2019, is a validation for Amgen’s drug discovery capabilities, analysts say.

The company’s launch of the drug will be closely watched by investors and analysts looking to see Amgen offset declining revenue from older products, including rheumatoid-arthritis drug Enbrel.

Related Posts

One Oil Company’s Rocky Path to Renewable Energy

June 8, 2021

June 8, 2021

For years, Danish Oil and Natural Gas Co. did what many other big oil companies do: pumped hydrocarbons out of...

SEC Is Running Out of Options to Rein In Elon Musk

June 2, 2021

June 2, 2021

WASHINGTON—The Securities and Exchange Commission has tried for several years to get Elon Musk to behave more like a typical...

Saudi Retail Magnate to List 432 Park Penthouse For as Much as $170 Million

June 28, 2021

June 28, 2021

Saudi retail and real-estate magnate Fawaz Al Hokair is planning to list his penthouse at 432 Park Avenue—one of New...

Teneo’s Declan Kelly, Crisis Manager for CEOs, Faces His Own Crisis

June 25, 2021

June 25, 2021

Declan Kelly, a go-to adviser for CEOs in crisis, is facing his own crisis. Mr. Kelly, chairman and chief executive...

Labor Shortage Draws Attention of U.S. Lawmakers

June 3, 2021

June 3, 2021

WASHINGTON—With millions of Americans still out of work and job openings at a record high, policy makers are dealing with...

4,368 Episodes Later, Conan O’Brien’s Late-Night Run Ends

June 24, 2021

June 24, 2021

Conan O’Brien’s farewell to late-night TV has reached its finale. His show “Conan” has been chockablock with his famous friends...

Democrats Wrestle Over Cost, Breadth of Antipoverty Plan

July 1, 2021

July 1, 2021

WASHINGTON—Democrats have no shortage of ideas about what they hope to include in their next big legislative package—subsidized child care,...

Spotify Eyes Top Podcaster Alexandra Cooper, ‘Call Her Daddy’ Show for $20 Million

June 11, 2021

June 11, 2021

Alexandra Cooper’s ‘Call Her Daddy’ was the fifth-most-popular podcast globally on Spotify last year. Photo: Mark Sagliocco/Getty Images for Gotham...

‘Friday’ Franchise Frozen as Ice Cube and Warner Bros. Fight Over New Movie

July 1, 2021

July 1, 2021

A spat between star Ice Cube and WarnerMedia has escalated into a high-stakes blame game that threatens to permanently derail...

Ransomware Group Behind Meat-Supply Attack Threatens Hundreds of New Targets

July 3, 2021

July 3, 2021

The ransomware group that collected an $11 million payment from meat producer JBS SA about a month ago has begun...

Stack Overflow Sold to Tech Giant Prosus for $1.8 Billion

June 2, 2021

June 2, 2021

Prosus PRX 0.54% NV said it struck a $1.8 billion deal to acquire Stack Overflow, an online community for software...

William Ackman SPAC Nears $40 Billion Universal Music Deal

June 3, 2021

June 3, 2021

Hedge-fund billionaire William Ackman’s special-purpose acquisition company is nearing a transaction with Universal Music Group that would value the world’s...

CFOs Plan to Reopen Offices But May Keep Some Pandemic Changes

June 7, 2021

June 7, 2021

Finance chiefs are drawing up plans to reopen their companies’ offices but want to stick to certain changes made during...

The Biggest Summer Travel Headaches and How to Avoid Them

May 26, 2021

May 26, 2021

Along with sunscreen and masks, you’re going to need to pack patience when you head out on your summer vacation....

AMC Boss Adam Aron Basks in Meme-Stock Spotlight

June 4, 2021

June 4, 2021

Adam Aron, AMC Entertainment Holdings Inc.’s AMC -6.68% chief executive, has decided to run with the meme-stock bulls who helped...